Aplicação do Cloprostenol Sódico em cabras leiteiras no puerpério

Abstract

This study assessed the of effects the application of cloprostenol in postpartum dairy goats. Twenty-nine Anglonubian goats were used, evenly divided into two groups. The control group received 0.5 ml of saline (0.9%) and group PGF2 0.133 mg cloprostenol in two intramuscular applications on day 1 (D1) and four (D4) PP. The reproductive tract of the animals was assessed by transrectal ultrasound with a linear, 5.0 MHz on days 1, 4, 10, 16, 22, 28, 34, 40 and 46 postpartum. The uterine diameter, cervical diameter, volume of the intrauterine contents and uterine position were measured. In four animals from each treatment the endometrial thickness and diameter of the two larger follicles present in the ovary were evaluated, and vaginoscopy revealed the presence and aspect of the cervical mucus. The data were tested using the ANOVA analysis of variance and the averages (uterine diameter and endometrial thickness), by the Tukey test. The position of the uterus was assessed by the X2 test (chi-square). The body condition score and volume of intrauterine contents were evaluated with the nonparametric Wilcoxon test. All parameters were considered significant at 5% probability level. The uterine diameter behaved differently between the groups. In the PGF2 group there was a marked reduction in uterine diameter until day 22 PP (3.5 ± 0.6 cm) and the control group until day 28 PP (3.6 ± 0.8 cm). The expulsion of uterine contents was earlier in PGF2 group (D40), and on D46 in the control group. Likewise, the presence of cervical mucus was earlier in PGF2 group (D34) compared to control group (D40). The follicular growth did not differ between the groups, the maximum average diameters were 5.1 ± 0.3 mm at 28 dpp for the PGF2 group and 5.2 ± 0.4 mm at 22 dpp for the control group. The results suggest that cloprostenol acts beneficially in the process of uterine involution and expulsion of uterine contents. Key-words: Goats, Uterine involution, Prostaglandin.